Early structural brain development in infants exposed to HIV and antiretroviral therapy <i>in utero</i> in a South African birth cohort — Catherine J. Wedderburn (2022) | RDL Network
Early structural brain development in infants exposed to HIV and antiretroviral therapy <i>in utero</i> in a South African birth cohort
Article 2022 en
Authors
CW
Catherine J. Wedderburn
NG
Nynke A. Groenewold
AR
Annerine Roos
Abstract
1 min read
Lower caudate and total grey matter volumes were found in infants who were HEU compared to HU in the first weeks of life, and maternal immunosuppression was associated with reduced volumes. These findings suggest that antenatal HIV exposure may impact early structural brain development and improved antenatal HIV management may have the potential to optimize neurodevelopmental outcomes of children who are HEU.
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