Brief summary: In this cross-sectional study, the growth pattern from birth until diagnosis of premature adrenarche (PA) was assessed in 82 children (16 boys) compared to 63 controls (15 boys). PA children were taller, heavier and had an accelerated linear growth. PA children also showed earlier adiposity rebound (AR) irrespective of whether they had obesity or not. A sex dimorphism was observed. The authors hypothesized that both earlier AR and accelerated linear growth may trigger adrenal androgen production and PA.
Emilia Koivuaho, Johanna Laru, Marja Ojaniemi, Katri Puukka, Johannes Kettunen, Juha S. Tapanainen, Stephen Franks, Paul M Ridker, Laure Morin‐Papunen, Sylvain Sebért, Terhi Piltonen
Ulla Sovio, Dennis O. Mook‐Kanamori, Nicole M. Warrington, Robert Lawrence, Laurent Briollais, Nicholette D. Palmer, Joanne E. Cecil, Johanna K. Sandling, Ann‐Christine Syvänen, Marika Kaakinen, Lawrence J. Beilin, Iona Y. Millwood, Amanda J. Bennett, Jaana Laitinen, Anneli Pouta, John Molitor, George Davey Smith, Yoav Ben‐Shlomo, Vincent W. V. Jaddoe, Lyle J. Palmer, Craig E. Pennell,
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