η6-(Arene)tricarbonylchromium and Manganese Complexes Linked to 2‘-Deoxyuridine

Mélanie Ethève‐Quelquejeu; Jean‐Philippe Tranchier; F. Rose‐Munch; Éric Rose; Lieve Naesens; De Clercq Erik

doi:10.1021/om700674v

Abstract

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Synthesis of η6-(arene)tricarbonylchromium and manganese complexes linked to 2‘-deoxyuridine via a triple-bond spacer is reported using palladium-catalyzed reactions of alkynes with halogeno derivatives, and their antiviral activity in cell-based assays studied.

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η<sup>6</sup>-(Arene)tricarbonylchromium and Manganese Complexes Linked to 2‘-Deoxyuridine