Dual targeting of cancer metabolome and stress antigens affects transcriptomic heterogeneity and efficacy of engineered T cells

Patricia Hernández-López; Eline van Diest; Péter Brázda; Sabine Heijhuurs; Angelo D. Meringa; Lauren Hoorens Van Heyningen; Caterina Riillo; Caroline Schwenzel; Marina Zintchenko; Inez Johanna; Mara J.T. Nicolasen; Astrid Cleven; Thomas A. Kluiver; Rosemary Millen; Jiali Zheng; Froso Karaiskaki; Trudy Straetemans; Hans Clevers; Remco de Bree; Hendrik G. Stunnenberg; Weng Chuan Peng; Jeanine Roodhart; Susana Minguet; Zsolt Sebestyén; Dennis X. Beringer; Jürgen Kuball

doi:10.1038/s41590-023-01665-0

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