Does effective diastolic coronary venous retroperfusion depend on arterial-like blood pressure in the coronary sinus?

In a number of studies, synchronized diastolic retroperfusion instituted 20 minutes after coronary artery occlusion has been shown to enhance recovery of regional contractile function.1–3 We hypothesized that, if retroperfusion was started before the onset of ischemia, it might prevent or at least delay the loss of regional function.