Do Statins Reduce the risk of Myocardial Infarction in Patients with Heart Failure? A Pooled Individual-Level Reanalysis of CORONA and GISSI-HF

This individual-level reanalysis of two landmark trials demonstrates a small but statistically significant decreased risk for MI among patients with ischaemic HF randomized to rosuvastatin vs. placebo. Rosuvastatin appears to be effective in preventing MI in ischaemic HF patients not already on statins.