Do overly complex reporting guidelines remove the focus from good clinical trials?

The ever increasing emphasis on complex reporting guidelines is getting in the way of designing and conducting good clinical trials, say <b>Jeremy Howick</b>, <b>Rebecca Webster</b>, and <b>J André Knottnerus</b>. But <b>David Moher</b> argues that, while following the guidelines can be frustrating, such complexity remains necessary and is improving research, not impeding it