The results of this study show that DTI is able to identify MS lesions with severe tissue damage and to detect changes in the NAWM. They also indicate that DTI-derived measures are correlated with clinical disability, especially in patients with secondary progressive MS, thus suggesting a role for DTI in monitoring advanced phases of the disease.
Maria A. Rocca, Mila Sonkin, Massimiliano Copetti, Elisabetta Pagani, Douglas L. Arnold, Sridar Narayanan, John G. Sled, Brenda Banwell, Massimo Filippi
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