Different Renal Function Equations and Dosing of Direct Oral Anticoagulants in Atrial Fibrillation

Yi‐Hsin Chan; Tze‐Fan Chao; Hsin‐Fu Lee; Yung‐Hsin Yeh; Shang‐Hung Chang; Chi‐Tai Kuo; Professor Gregory Lip; Shih‐Ann Chen

doi:10.1016/j.jacasi.2021.11.006

Abstract

1 min read

The adoptions of MDRD or CKD-EPI rather than CG would result in inappropriate dosing of DOACs (mainly overdosing), which would attenuate the advantages of DOACs compared to warfarin. The CG equation should be used as the gold standard to calculate eGFRs and guide the DOAC dosages.

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