Differences in outcomes between oral anticoagulation “new starters” and “switchers” in patients with nonvalvular atrial fibrillation: A pooled analysis of the AMADEUS and BOREALIS trials

In this post hoc analysis of clinical trial patients with AF, "new starters" and "switchers" for VKA initiation had nonstatistically significant rates of trial-adjudicated thromboembolism, major bleeding, and all-cause mortality.