Dietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression

Eek Joong Park; Jun Hee Lee; Guann‐Yi Yu; Guobin He; Syed R. Ali; Ryan G. Holzer; Christoph H. Österreicher; Hiroyuki Takahashi; Michael Karin

doi:10.1016/j.cell.2009.12.052

Related publications

Article2013

Inflammation and liver tumorigenesis

Beicheng Sun, Michael Karin

Article2020

Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis

Yun Liao, Junjie Zhao, Katarzyna Bulek, Fangqiang Tang, Xing Chen, Gang Cai, Shang Jia, Paul L. Fox, Emina H. Huang, Theresa T. Pizarro, Matthew F. Kalady, Mark W. Jackson, Shideng Bao, Ganes C. Sen, George R. Stark, Christopher J Chang, Xiaoxia Li

Article2011

Obesity, inflammation, and liver cancer

Beicheng Sun, Michael Karin

Article1990

Biology of multifunctional cytokines: IL 6 and related molecules (IL 1 and TNF)

Akira Shizuo, Toshio Hirano, Tetsuya Taga, Tadamitsu Kishimoto

The FASEB Journal

Article2014

Liver Damage, Inflammation, and Enhanced Tumorigenesis after Persistent mTORC1 Inhibition

Atsushi Umemura, Eek Joong Park, Koji Taniguchi, Jun Hee Lee, Shabnam Shalapour, Mark A. Valasek, Mariam Aghajan, Hayato Nakagawa, Ekihiro Seki, Michael N. Hall, Michael Karin