In this paper we investigate the performance of statistical modeling of digital mammograms by means of wavelet domain hidden Markov tree model (WHMT) for its inclusion to a computer-aided diagnostic prompting system for detecting microcalcification (MC) clusters. The system incorporates: (1) gross-segmentation of mammograms for obtaining the breast region; (2) eliminating the pepper-type noise, (3) block-wise wavelet transform of the breast signal and likelihood calculation; (4) image segmentation; (5) postprocessing for retaining MC clusters. FROC curves are obtained for all MC clusters containing mammograms of mini-MIAS database. 100% of true positive cases are detected by the system at 2.9 false positives per case
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