DESMOPRESSIN FOR NOCTURNAL INCONTINENCE IN THE SPINA BIFIDA POPULATION

No AccessJournal of UrologyPediatric Urology1 Dec 1997DESMOPRESSIN FOR NOCTURNAL INCONTINENCE IN THE SPINA BIFIDA POPULATION Mark Horowitz, Andrew J. Combs, and Dawn Gerdes Mark HorowitzMark Horowitz More articles by this author , Andrew J. CombsAndrew J. Combs More articles by this author , and Dawn GerdesDawn Gerdes More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)68232-6AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We report our experience with the use of desmopressin in the spina bifida population that is dry during the day but wet at night. Materials and Methods: From 1994 to 1996, 18 patients with myelodysplasia were treated with desmopressin for persistent nocturnal enuresis. Initial dose was 40 mcg. before bedtime, decreased by intervals of 10 mcg. every 3 weeks. Patients were kept on the minimum dose required to keep them dry. We reviewed morning catheterized volumes, side effects and dosages needed to stay dry, and compared augmented patients with nonaugmented patients. Results: Of 18 patients 14 (78%) reported marked improvement in nocturnal enuresis. Of 6 augmented patients 5 (83%) are dry compared to 9 of 12 nonaugmented patients (75%). There were no adverse side effects from the use of desmopressin. Average dose to stay dry was 20 mcg. for augmented and 30 mcg. for nonaugmented patients. Of the 4 patients who had persistent nocturnal incontinence despite desmopressin 3 (75%) became dry with a single catheterization in the middle of the night. Conclusions: Desmopressin is successful in treating nocturnal enuresis in the spina bifida patient with diurnal continence. References 1 : DDAVP in the urological management of the difficult neurogenic bladder in spinal cord injury: preliminary report.. J. Amer. Paraplegia Soc.1994; 17: 165. Google Scholar From the State University of New York Health Science Center at Brooklyn, Brooklyn, New York.Accepted for publication June 27, 1997.(Horowitz) Requests for reprints: 450 Clarkson Ave., Box 79, Brooklyn, New York 11203.© 1997 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byDEL GADO R, ACETO G, DEL GAIZO D, DEL GADO G, POLIDORI G and CHIOZZA M (2018) DESMOPRESSIN FOR THE TREATMENT OF NOCTURNAL BEDWETTING IN PATIENTS WITH NEURAL TUBE CLOSURE DEFECTSJournal of Urology, VOL. 171, NO. 4, (1656-1658), Online publication date: 1-Apr-2004. Volume 158Issue 6December 1997Page: 2267-2268 Advertisement Copyright & Permissions© 1997 by American Urological Association, Inc.Metrics Author Information Mark Horowitz More articles by this author Andrew J. Combs More articles by this author Dawn Gerdes More articles by this author Expand All Advertisement PDF downloadLoading ...