Design, Synthesis and Structure-Activity Relationships of Novel HIV Capsid Inhibitors with Potent Antiviral Activities

Dazhou Shi; Shujing Xu; Lin Sun; Prem P. Sharma; Brijesh Rathi; Mei Wang; Linan Wu; Xiangyi Jiang; De Clercq Erik; Christophe Pannecouque; Xinyong Liu; Alexej Dick; Peng Zhan

doi:10.2139/ssrn.5200966

Related publications

Article2025

Design, synthesis and structure-activity relationships of novel HIV capsid inhibitors with potent antiviral activities

Dazhou Shi, Shujing Xu, Lin Sun, Prem P. Sharma, Brijesh Rathi, Mei Wang, Linan Wu, Xiangyi Jiang, De Clercq Erik, Christophe Pannecouque, Xinyong Liu, Alexej Dick, Shujing Xu

Article2020

Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV-1 Capsid Inhibitors with Improved Antiviral Activities

Lin Sun, Alexej Dick, Megan E. Meuser, Tianguang Huang, Waleed A. Zalloum, Chin‐Ho Chen, Srinivasulu Cherukupalli, Shujing Xu, Xiao Ding, Ping Gao, Dongwei Kang, De Clercq Erik, Christophe Pannecouque, Simon Cocklin, Kuo‐Hsiung Lee, Xinyong Liu, Peng Zhan

Article2022

Design, Synthesis and Structure—Activity Relationships of Phenylalanine-Containing Peptidomimetics as Novel HIV-1 Capsid Binders Based on Ugi Four-Component Reaction

Xiangkai Ji, Jing Li, Prem P. Sharma, Xiangyi Jiang, Brijesh Rathi, Zhen Gao, Lide Hu, Dongwei Kang, De Clercq Erik, Simon Cocklin, Chuanfeng Liu, Christophe Pannecouque, Alexej Dick, Xinyong Liu, Peng Zhan

Article2021

Design, synthesis, and mechanism study of dimerized phenylalanine derivatives as novel HIV-1 capsid inhibitors

Xujie Zhang, Lin Sun, Megan E. Meuser, Waleed A. Zalloum, Shujing Xu, Tianguang Huang, Srinivasulu Cherukupalli, Xiangyi Jiang, Xiao Ding, Yucen Tao, Dongwei Kang, De Clercq Erik, Christophe Pannecouque, Alexej Dick, Simon Cocklin, Xinyong Liu, Peng Zhan

Article2009

Design, Synthesis and SAR of New Potent HIV-1 RT Inhibitors

Alba Chimirri, De Clercq Erik, Giovanni Maga, Patrizia Logoteta, Stefania Ferro, Laura De Luca, Nunzio Iraci, Christophe Pannecouque, Anna‐Maria Monforte