Design, synthesis, and biological evaluation of novel double-winged galloyl derivatives as HIV-1 RNase H inhibitors

Lina Zhang; Fenju Wei; David Borrego; Fabao Zhao; Javier Martínez del Río; Estrella Frutos-Beltrán; Jiwei Zhang; Shujing Xu; Nerea López‐Carrobles; Shenghua Gao; Dongwei Kang; Christophe Pannecouque; De Clercq Erik; Xinyong Liu; Luis Menéndez‐Arias; Peng Zhan

doi:10.1016/j.ejmech.2022.114563

Related publications

Article2025

Design, Synthesis and Biological Evaluation of 3-Hydrazonoindolin-2-one Derivatives as Novel HIV-1 RNase H Inhibitors

Yiying Zhang, Robert Wang, Yang Bu, Angela Corona, Laura Dettori, Enzo Tramontano, Christophe Pannecouque, De Clercq Erik, Shuai Wang, Ge Meng, Fen‐Er Chen

Article2018

Design, synthesis, and biologic evaluation of novel galloyl derivatives as <scp>HIV</scp>‐1 <scp>RN</scp>ase H inhibitors

Ping Gao, Xueshun Wang, Lin Sun, Xiqiang Cheng, Vasanthanathan Poongavanam, Jacob Kongsted, Mar Álvarez, Joanna Luczkowiak, Christophe Pannecouque, De Clercq Erik, Kuo‐Hsiung Lee, Chin‐Ho Chen, Huiqing Liu, Luis Menéndez‐Arias, Xinyong Liu, Peng Zhan

Article2024

Design, synthesis and biological evaluation of Thiazolo[3, 2-a]Pyrimidine derivatives as novel RNase H inhibitors

Kexin Zhao, Yiying Zhang, J. Wang, Shuai Wang, Angela Corona, Stefania Maloccu, Enzo Tramontano, Christophe Pannecouque, De Clercq Erik, Ge Meng, Lei Wang, Fen‐Er Chen

Article2013

Synthesis and biological evaluation of pyridazine derivatives as novel HIV-1 NNRTIs

Dongyue Li, Peng Zhan, Huiqing Liu, Christophe Pannecouque, Jan Balzarini, De Clercq Erik, Xinyong Liu

Article2021

Boronic acid-containing diarylpyrimidine derivatives as novel HIV-1 NNRTIs: Design, synthesis and biological evaluation

Da Feng, Fenju Wei, Yanying Sun, Prem P. Sharma, Tao Zhang, Hao Lin, Brijesh Rathi, De Clercq Erik, Christophe Pannecouque, Dongwei Kang, Peng Zhan, Xinyong Liu