Dementia risk in patients with type 2 diabetes: Comparing metformin with no pharmacological treatment
Article 2023 en
Authors
BZ
Bang Zheng
BS
Bowen Su
SA
Sara Ahmadi‐Abhari
Abstract
1 min read
Metformin initiators had a significantly lower risk of dementia compared with patients not receiving anti-diabetes medication. Compared with metformin initiators, diabetes patients not receiving pharmacological treatment had better glycemic profiles at baseline and during follow-up. Patients on long-term metformin treatment had an even lower risk of subsequent dementia incidence. Metformin may act beyond its effect on hyperglycemia and has the potential of being repurposed for dementia prevention.
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Konstantinos K. Tsilidis, Despoina Capothanassi, Naomi E. Allen, Evangelos C. Rizos, David López-Valencia, Karin van Veldhoven, Carlotta Sacerdote, Deborah Ashby, Paolo Vineis, Ioanna Tzoulaki, John P A Ioannidis
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