In patients with multiple myeloma, completion of mRNA-based vaccination schemes failed to yield detectable SARS-CoV-2 Omicron-neutralizing antibodies and S1-RBD-specific CD8+ T cells in approximately 60% and 80% of the cases, respectively. Patients who develop breakthrough infections exhibited very low levels of live-virus neutralizing antibodies and the absence of follicular T helper cells. See related article by Azeem et al., p. 106 (9). See related article by Chang et al., p. 1684 (10).
Cristina Bergamaschi, Maria Pagoni, Margherita Rosati, Matthew Angel, Ifigeneia Tzannou, Margarita Vlachou, Ismini Darmani, Amirah Ullah, Jenifer Bear, Santhi Devasundaram, Robert Burns, Ioannis Baltadakis, Stavros Gigantes, Meletios A Dimopoulos, George N. Pavlakis, Evangelos Terpos, Barbara K. Felber
Margherita Rosati, Evangelos Terpos, Mahesh Agarwal, Vangelis Karalis, Jenifer Bear, Robert Burns, Xintao Hu, Demetrios G. Papademetriou, Ioannis Ntanasis‐Stathopoulos, Ioannis P. Trougakos, Meletios A Dimopoulos, George N. Pavlakis, Barbara K. Felber
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