<ns3:p>Background: Mapping time-structures is a burgeoning scientific field enriching the (P4) medicine models. Local evidence in Mediterranean populations is underinvestigated. Methods: The Censused stroke-related death events (D) in the largest East-Mediterranean port (Piraeus), during (1985-1989), when local population had diet (low fat/sugar, proteins and vegetables/fruits daily, and pure olive oil almost exclusively) and genetic homogeneity-later interrupted by the immigration into Greece in 1990; and Sunspot numbers were indexed by Wolf numbers (Rz) (1944-2004), and evaluated using Fast Fourier Analysis and Singular Spectrum Analysis in MATLAB. Results: D were turned with fluctuations >35% in Rz. A non-anthropogenic 6.8 days cycle was recognized. Conclusions: This study may be taken into consideration in future public health planning and chronotherapy evaluations.</ns3:p>
Masafumi Ono, Hideyuki Kawashima, Hironori Hara, Neil O’Leary, Chao Gao, Rutao Wang, Kuniaki Takahashi, Joanna J. Wykrzykowska, Jan J. Piek, Michael J. Mack, David R. Holmes, Marie-Claude Morice, Stuart J. Head, A. Pieter Kappetein, Daniel J.F.M. Thuijs, Thilo Noack, Mohr W. Friedrich, Piroze Davierwala, John W. McEvoy, Yoshinobu Onuma, Patrick W. Serruys
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