Cubic spline for the association between OPN levels and HCC from Circulating Osteopontin and Prediction of Hepatocellular Carcinoma Development in a Large European Population

<p>Multivariable adjusted odds ratio (continuous line) and 95% CI (dotted line) are shown for the continuous levels of OPN values associated to HCC. Reference value was set at 47.15 ng/ml (the optimal cut-off point) for all subjects. For better visibility, the levels were truncated at 1 and 99 percentile of distribution.</p>