CRISPR engineering in organoids for gene repair and disease modelling

Maarten H. Geurts, Eyleen de Poel, Cayetano Pleguezuelos‐Manzano, Rurika Oka, Léo Carrillo, Amanda Andersson-Rolf, Matteo Boretto, Jesse E Brunsveld, Ruben van Boxtel, Jeffrey M. Beekman, Hans Clevers

Preprint2020

Evaluating CRISPR-based Prime Editing for cancer modeling and CFTR repair in intestinal organoids

Maarten H. Geurts, Eyleen de Poel, Cayetano Pleguezuelos‐Manzano, Léo Carrillo, Amanda Andersson-Rolf, Matteo Boretto, Jeffrey M. Beekman, Hans Clevers

Article2017

CRISPR-Induced TMPRSS2-ERG Gene Fusions in Mouse Prostate Organoids.

Else Driehuis, Hans Clevers

Article2017

CRISPR-Induced TMPRSS2-ERG Gene Fusions in Mouse Prostate Organoids.

Else Driehuis, Hans Clevers

Article2022

Differentiation and CRISPR-Cas9-mediated genetic engineering of human intestinal organoids

Adriana Martínez-Silgado, Fjodor A. Yousef Yengej, Jens Puschhof, Veerle Geurts, Charelle Boot, Maarten H. Geurts, Maarten B Rookmaaker, Marianne C. Verhaar, Joep Beumer, Hans Clevers

Created:

June 19, 2026