Creating ATP via creatine kinase B for NLRP3 activation

Juliana E. Toller-Kawahisa; Luke O'neill

doi:10.1038/s41590-022-01191-5

Article2014

Control of the human Th1 response via autocrine complement-regulated NLRP3 inflammasome activation within CD4(+) T cells

Giuseppina Arbore, Antonella F. Fara, Rebecca C. Coll, Avril A. B. Robertson, Matthew Cooper, Luke O'neill, Paul Lavender, Andrew P. Cope, Helen J. Lachmann, Claudia Kemper

Molecular Immunology

Preprint2021

Engineering diaminotriazole ligands into ATP-mimetics for selective targeting of the Janus kinase 2 (JAK2) pseudokinase domain (JH2)

Maria-Elena Liosi, Stefan Krimmer, Ana S. Newton, Thomas L. Dawson, David A. Puleo, Kara J. Cutrona, Yoshihisa Suzuki, Sean Henry, Joseph Schlessinger, William L. Jorgensen

Article2013

Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome

Takuma Misawa, Michihiro Takahama, Tatsuya Kozaki, Hanna Lee, Jian Zou, Tatsuya Saitoh, Akira Shizuo

Nature Immunology

Article2013

TAB3 in B Cell Activation via MAPKs Polyubiquitin-Binding Proteins TAB2 and Essential Roles of K63-Linked

Takashi Mino, Akira Shizuo, Osamu Takeuchi, Daisuke Ori, Hiroki Kato, Hideki Sanjo, Sarang Tartey

Article2010

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

Seth L. Masters, Aisling Dunne, Shoba Subramanian, Rebecca L. Hull, Gillian M. Tannahill, Fiona A. Sharp, Christine Becker, Luigi Franchi, Eiji Yoshihara, Zhe Chen, N Mullooly, Lisa A. Mielke, James Harris, Rebecca C. Coll, Kingston H. G. Mills, K. Hun Mok, Philip Newsholme, Gabriel Nuñez, Junji Yodoi, Steven E. Kahn, Ed C. Lavelle, Luke O'neill

Nature Immunology

Creating ATP via creatine kinase B for NLRP3 activation

Abstract

Discussion(0)

Related publications

Control of the human Th1 response via autocrine complement-regulated NLRP3 inflammasome activation within CD4(+) T cells

Engineering diaminotriazole ligands into ATP-mimetics for selective targeting of the Janus kinase 2 (JAK2) pseudokinase domain (JH2)

Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome

TAB3 in B Cell Activation via MAPKs Polyubiquitin-Binding Proteins TAB2 and Essential Roles of K63-Linked

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes