Cortical thickness in obsessive–compulsive disorder: Multisite mega-analysis of 780 brain scans from six centres
Article 2016 en
Authors
JF
Jean-Paul Fouche
SP
Stéfan du Plessis
CH
Coenie Hattingh
Abstract
1 min read
Our findings are partially consistent with earlier work, suggesting that group differences in grey matter volume and cortical thickness could relate to the same underlying pathology of OCD. They partially support a frontostriatal model of OCD, but also suggest that limbic, temporal and parietal regions play a role in the pathophysiology of the disorder. The group × age interaction effects may be the result of altered neuroplasticity.
Stella J. de Wit, Pino Alonso, Lizanne Schweren, David Mataix‐Cols, Christine Löchner, José M. Menchón, Dan Joseph Stein, Jean-Paul Fouche, Carles Soriano‐Mas, João Ricardo Sato, Marcelo Q. Hoexter, Damiaan Denys, Takashi Nakamae, Seiji Nishida, Jun Soo Kwon, Geraldo F. Busatto, Narcı́s Cardoner, Daniëlle C. Cath, Kenji Fukui, Wi Hoon Jung, Sung Nyun Kim, Eurı́pedes Constantino Miguel, Jin Narumoto, Mary L. Phillips, Jesús Pujol, Peter L. Remijnse, Yuki Sakai, Na Young Shin, Kei Yamada, Dick J. Veltman, Odile A. van den Heuvel
Stella J. de Wit, Pino Alonso, Lizanne Schweren, David Mataix‐Cols, Christine Löchner, José M. Menchón, Dan Joseph Stein, Jean‐Paul Fouché, Carles Soriano‐Mas, João Ricardo Sato, Marcelo Q. Hoexter, Damiaan Denys, Takashi Nakamae, Seiji Nishida, Jun Soo Kwon, Joon Hwan Jang, Geraldo F. Busatto, Narcı́s Cardoner, Daniëlle C. Cath, Kenji Fukui, Wi Hoon Jung, Sung Nyun Kim, Eurı́pedes Constantino Miguel,
Carles Soriano‐Mas, Gianfranco Spalletta, Michael C. Stevens, Philip R. Szeszko, David F. Tolin, Guido van Wingen, Ganesan Venkatasubramanian, Zhen Wang, Je‐Yeon Yun, Paul M. Thompson, Dan Joseph Stein, Pino Alonso, Stephanie H. Ameis, Alan Anticevic, Paul Arnold, Núria Bargalló, Marcelo C. Batistuzzo, Francesco Benedetti, Jan C. Beucke, Irene Bollettini, Anushree Bose, ,
Yash Patel, Nadine Parker, Jean Shin, Derek Howard, Leon French, Sophia I. Thomopoulos, Elena Pozzi, Daan van Rooij, Jan K. Buitelaar, Martine Hoogman, Barbara Franke, Ole A. Andreassen, Margaret J. Wright, Christopher R. K. Ching, Lianne Schmaal, Dick J. Veltman, Odile A. van den Heuvel, Dan Joseph Stein, Jessica A. Turner, Neda Jahanshad, Tomáš Paus
Discussion(0)
No comments yet. Be the first to comment.