Converging biofabrication and organoid technologies: the next frontier in hepatic and intestinal tissue engineering? — Kerstin Schneeberger (2017) | RDL Network
Converging biofabrication and organoid technologies: the next frontier in hepatic and intestinal tissue engineering?
Article 2017 en
Authors
KS
Kerstin Schneeberger
BS
Bart Spee
PC
Pedro Costa
Abstract
1 min read
Adult tissue stem cells can form self-organizing 3D organoids in vitro. Organoids resemble small units of their organ of origin and have great potential for tissue engineering, as well as models of disease. However, current culture technology limits the size, architecture and complexity of organoids. Here, we review the establishment of intestinal and hepatic organoids and discuss how the convergence of organoids and biofabrication technologies can help overcome current limitations, and thereby further advance the translational application of organoids in tissue engineering and regenerative medicine.
Laura Rijns, Joost A. P. M. Wijnakker, Victor A. Veenbrink, Riccardo Bellan, Fenna W. B. Craenmehr, Simone I. S. Hendrikse, Johnick F. van Sprang, Wim de Lau, E.W. Meijer, Hans Clevers, Patricia Y W Dankers, Laura Rijns, Joost A. P. M. Wijnakker, Victor A. Veenbrink, Riccardo Bellan, Fenna W. B. Craenmehr, Simone I. S. Hendrikse, Johnick F. van Sprang, Wim de Lau, E.W. Meijer, Hans Clevers, Patricia Y W Dankers
Nicola Elvassore, Anna Urciuolo, Giovanni Giuseppe Giobbe, Yixiao Dong, Federica Michielin, Luca Brandolino, Michael Magnussen, Onelia Gagliano, Giulia Selmin, Valentina Scattolini, Paolo Raffa, Soichi Shibuya, Xuechun Wang, Ju Qu, Marko Nikolić, Marco Montagner, Hans Clevers, Monica Giomo, Paolo De Coppi
Discussion(0)
No comments yet. Be the first to comment.