Continuous renal replacement therapy (CRRT) has become the preferred dialysis modality to support critically ill children with acute kidney injury. As CRRT technology and clinical practice advances, experiences using CRRT on small infants and neonates have increased. In neonates with hyperammonemia or acute kidney injury during extracorporeal membrane oxygenation (ECMO) therapy, CRRT can be a safe and effective technique. However, there are many limitations of CRRT in neonates, including vascular access, bleeding complications, and lack of neonatespecific devices. This review discusses the basic principles of CRRT and the special considerations when using this technique in neonates and infants.
Mauro Neri, Gianluca Villa, Francesco Garzotto, Sean M. Bagshaw, Rinaldo Bellomo, Jorge Cerdá, Fiorenza Ferrari, Silvia Guggia, Michael Joannidis, John A. Kellum, Jeong Chul Kim, Ravindra L. Mehta, Zaccaria Ricci, Alberto Trevisani, Silvio Marafon, William R. Clark, Jean Louis Vincent, Claudio Ronco
Gianluca Villa, Mauro Neri, Rinaldo Bellomo, Jorge Cerdá, Angelo Raffaele De Gaudio, Silvia De Rosa, Francesco Garzotto, Patrick M. Honoré, John A. Kellum, Anna Lorenzin, Didier Payen, Zaccaria Ricci, Sara Samoni, Jean Louis Vincent, Julia Wendon, Marta Zaccaria, Claudio Ronco
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