Confirmation of Sentinel Lymph Node Identity by Analysis of Fine-Needle Biopsy Samples Using Inductively Coupled Plasma–Mass Spectrometry
Article 2008 en
Authors
AB
Alison Beavis
MD
Michael J. Dawson
PD
Philip Doble
Abstract
1 min read
Our results show that ICP-MS analysis of antimony concentrations in FNB specimens from lymph nodes can accurately confirm the identity of SLNs. Used in conjunction with techniques such as proton magnetic resonance spectroscopy for the nonsurgical evaluation of SLNs, ICP-MS analysis of antimony concentrations in FNB samples could potentially serve as a minimally invasive alternative to surgery and histopathologic evaluation to objectively classify a given node as sentinel or nonsentinel and determine its tumor-harboring status.
Rajmohan Murali, Anna Doubrovsky, Geoffrey Watson, Paul McKenzie, C. Lee, Duncan McLeod, Roger F. Uren, Jonathan R. Stretch, Robyn P.M. Saw, John F. Thompson, Richard A Scolyer
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