Comparison of lumefantrine, mefloquine, and piperaquine concentrations between capillary plasma and venous plasma samples in pregnant women with uncomplicated falciparum and vivax malaria — Makoto Saito (2024) | RDL Network
Comparison of lumefantrine, mefloquine, and piperaquine concentrations between capillary plasma and venous plasma samples in pregnant women with uncomplicated falciparum and vivax malaria
Antimicrobial Agents and Chemotherapy 68(5)
Article 2024 English
Authors
MS
Makoto Saito
PW
Pornpimon Wilaisrisak
MP
Mupawjay Pimanpanarak
Abstract
1 min read
Capillary samples offer practical benefits compared with venous samples for the measurement of drug concentrations, but the relationship between the two measures varies between different drugs. We measured the concentrations of lumefantrine, mefloquine, piperaquine in 270 pairs of venous plasma and concurrent capillary plasma samples collected from 270 pregnant women with uncomplicated falciparum or vivax malaria. The median and range of venous plasma concentrations included in this study were 447.5 ng/mL (8.81-3,370) for lumefantrine (day 7,
Elizabeth A. Ashley, Kasia Stepniewska, Niklas Lindegårdh, Anna Annerberg, Joel Tärning, Rose McGready, Lucy Phaiphun, Pratap Singhasivanon, Sir Nicholas White, François Nosten
Joel Tärning, Rose McGready, Niklas Lindegårdh, Elizabeth A. Ashley, Mupawjay Pimanpanarak, Benjamas Kamanikom, Anna Annerberg, Nicholas Day, Kasia Stepniewska, Pratap Singhasivanon, Sir Nicholas White, François Nosten
Marcus J. Rijken, Rose McGready, Aung Pyae Phyo, Niklas Lindegårdh, Joel Tärning, Natthapon Laochan, Hla Hla Than, Oh Mu, Aye Kyi Win, Pratap Singhasivanon, Sir Nicholas White, François Nosten
Makoto Saito, Mary Ellen Gilder, Verena I. Carrara, Laypaw Archusuksan, Hsa Eh, Naw Eh, Ma Ner, Aye Kyi Win, Laaongsri Niwetphongprai, Urairat Koesukwiwat, Joel Tärning, Sir Nicholas White, François Nosten, Rose McGready
Discussion(0)
No comments yet. Be the first to comment.