Comparative efficacy and safety of Traditional Chinese Patent Medicine for Anxiety disorders in children or adolescence — A Bayesian network meta-analysis protocol

Review question / Objective: Chinese patent medicines play an irreplaceable role in the treatment of this disease.At present, there is no comparison of the safety and effectiveness of various Chinese patent medicines curing anxiety in adolescents.So we take advantage of the method of network meta-analysis to systematically compare the efficacy of various Chinese patent medicines curing this disease.Condition being studied: Anxiety is the appearance of inner fear and restlessness for no obvious reason, often accompanied by autonomic dysfunction, and the clinical symptoms are persistent mental stress or episodic panic.Adolescents and children are in a special period of physical and mental development.Due to their young age and poor mental endurance, they are vulnerable to adverse life events.Therefore, Anxiety symptoms are very common especially in adolescents and children.Relevant research shows that about 5%-20% of children and adolescents worldwide have anxiety disorders; A Norwegian survey on the stability, changes and incidence of anxiety symptom clusters among 13-16-year-olds found that the incidence of high-level anxiety was 8.2%.Children suffering from anxiety disorders are vulnerable to other mental problems and related physical symptoms in the later growth process than other children.