Comments on “Low-dose aspirin for preventing intrauterine growth restriction and pre-eclampsia in sickle cell pregnancy in Nigeria (PIPSICKLE): a randomised controlled trial”

Sistiana Aiello; Ariela Benigni; Giuseppe Remuzzi

doi:10.4081/btvb.2026.463

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Giuseppe Remuzzi

Comments on “Low-dose aspirin for preventing intrauterine growth restriction and pre-eclampsia in sickle cell pregnancy in Nigeria (PIPSICKLE): a randomised controlled trial”

Article 2026 en

Authors

SA
Sistiana Aiello
AB
Ariela Benigni
Giuseppe Remuzzi

Abstract

1 min read

In the early 1970s, aspirin (acetylsalicylic acid) was shown to inhibit platelet aggregation by irreversibly acetylating platelet cyclooxygenase (COX), thereby suppressing the synthesis of its pro-aggregating product thromboxane A₂ (TxA₂)...

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Comments on “Low-dose aspirin for preventing intrauterine growth restriction and pre-eclampsia in sickle cell pregnancy in Nigeria (PIPSICKLE): a randomised controlled trial”

Abstract

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