Anaemia is a common problem in critically ill patients admitted to intensive care units. Many factors can be involved in its development, including rapid alterations in iron metabolism. Maintenance of iron homeostasis is a prerequisite for many essential biological processes and is a central element for the development of erythroid precursors and mature red blood cells. With the inflammatory process, iron distribution is disturbed, with decreased serum iron levels and increased iron stores. Little information is available on the precise role of alterations in iron metabolism in the development of iron anaemia in critically ill patients.
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