accurately distinguish them before the determination of therapy (i.e., liver transplantation). Our data show that the application of the American Association for the Study of Liver Diseases guidelines prevents a false-positive diagnosis of ICC in cirrhosis. Small ICC may display an early enhancement (partial or total) in the arterial phase. This is similar to the HCC pattern, but because we have not observed washout in delayed phases, this finding is confirmed to be specific for HCC 2,3 and critical for nodule diagnosis.
Arndt Vogel, Andrés Cervantes, Ian Chau, Bruno Daniele, Josep M. Llovet, Tim Meyer, Jean‐Charles Nault, Ulf P. Neumann, Jens Ricke, Bruno Sangro, Peter Schirmacher, Chris Verslype, Francis Zech, Dirk Arnold, Erika Martinelli
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