Coexistent Wegener’s Granulomatosis and Goodpasture’s Disease: What Is the Mechanism?

To the Editor: We read with interest the article by Mulpuru, et al 1. They described a 50-year-old woman who developed Goodpasture’s disease one month after the diagnosis of Wegener’s granulomatosis1. As one of the possible mechanisms, they described that antineutrophil cytoplasmic antibody (ANCA) might initiate renal damage, which exposes the glomerular basement membrane (GBM) as an antigenic source, allowing the development of … Address correspondence to Dr. Kim; E-mail: kkkjhd{at}yuhs.ac