Clinical Activity of Ripretinib in Patients with Advanced Gastrointestinal Stromal Tumor Harboring Heterogeneous <i>KIT/PDGFRA</i> Mutations in the Phase III INVICTUS Study — Sebastian Bauer (2021) | RDL Network
Clinical Activity of Ripretinib in Patients with Advanced Gastrointestinal Stromal Tumor Harboring Heterogeneous <i>KIT/PDGFRA</i> Mutations in the Phase III INVICTUS Study
Article 2021 en
Authors
SB
Sebastian Bauer
MH
Michael C. Heinrich
SG
Suzanne George
Abstract
1 min read
Ripretinib provided clinically meaningful activity across mutation subgroups in patients with advanced GIST, demonstrating that ripretinib inhibits a broad range of <i>KIT/PDGFRA</i> mutations in patients with advanced GIST who were previously treated with three or more TKIs.
Sebastian Bauer, Michael C. Heinrich, Suzanne George, John Zalcberg, César Serrano, Hans Gelderblom, Robin L. Jones, Steven Attia, Gina Z. D’Amato, Ping Chi, Peter Reichardt, Julie Meade, Ying Su, Rodrigo Ruiz‐Soto, Jean Yves Blay, Margaret von Mehren, Patrick Schöffski
Sebastian Bauer, Michael C. Heinrich, Suzanne George, John Zalcberg, César Serrano, Hans Gelderblom, Robin L. Jones, Steven Attia, Gina Z. D’Amato, Ping Chi, Peter Reichardt, Julie Meade, Ying Su, Rodrigo Ruiz‐Soto, Jean Yves Blay, Margaret von Mehren, Patrick Schöffski
Suzanne George, Jean Yves Blay, Ping Chi, Robin L. Jones, César Serrano, Neeta Somaiah, Hans Gelderblom, John Zalcberg, William M. Reichmann, Kam Sprott, P. H. Cox, Matthew L. Sherman, Rodrigo Ruiz‐Soto, Michael C. Heinrich, Sebastian Bauer
Sebastian Bauer, Robin L. Jones, Suzanne George, Hans Gelderblom, Patrick Schöffski, Margaret von Mehren, John Zalcberg, Yoon‐Koo Kang, Albiruni Ryan Abdul Razak, Jonathan C. Trent, Steven Attia, Axel Le Cesne, William M. Reichmann, Kam Sprott, Haroun Achour, Matthew L. Sherman, Rodrigo Ruiz‐Soto, Jean Yves Blay, Michael C. Heinrich
Jonathan C. Trent, Robin L. Jones, Suzanne George, Hans Gelderblom, Patrick Schöffski, Margaret von Mehren, John Zalcberg, Yoon‐Koo Kang, Albiruni Ryan Abdul Razak, Steven Attia, Axel Le Cesne, William M. Reichmann, Kam Sprott, Haroun Achour, Matthew L. Sherman, Rodrigo Ruiz‐Soto, Jean Yves Blay, Michael C. Heinrich, Sebastian Bauer
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