The cisplatin, ifosfamide, methotrexate and vinblastine regimen appeared active in patients with metastatic urothelial carcinoma. This regimen was associated with significant but manageable hematological toxicity and the incidence of mucositis or renal impairment was low. Prospective randomized studies are needed to assess whether the addition of ifosfamide to other active agents will improve the survival of patients with this disease.
Zacharias Kyriakakis, Meletios A Dimopoulos, A. Kostakopoulos, Aristidis Karayiannis, F. Sofras, Anastasios Zervas, Aristidis Giannopoulos, C Dimopoulos
Aristotle Bamias, G. Lainakis, Efstathios Kastritis, Nikos Antoniou, G. Alivizatos, Ανδρέας Κουρέας, Michael Chrisofos, Andreas Skolarikos, Evangelos Karayiotis, Meletios A Dimopoulos
Aristotelis Bamias, Efstathios Kastritis, George Bozas, Vassiliki Koutsoukou, N. Antoniou, H. Katsifotis, K. Konstantinidis, Andreas Skolarikos, C. Deliveliotis, Meletios A Dimopoulos
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