Chronic Intermittent Hypoxia Induces Atherosclerosis via Activation of Adipose Angiopoietin-like 4

Luciano F. Drager; Qiaoling Yao; Karen Hernandez; Mi-Kyung Shin; Shannon Bevans‐Fonti; Jason Gay; Thomas E. Sussan; Jonathan C. Jun; Allen C. Myers; Gunilla Olivecrona; Alan R. Schwartz; Nils Halberg; Philipp E. Scherer; Gregg L. Friedman; David R. Powell; Vsevolod Y. Polotsky

doi:10.1164/rccm.201209-1688oc

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Chronic Intermittent Hypoxia Induces Atherosclerosis via Activation of Adipose Angiopoietin-like 4

Article 2013 en

Abstract

1 min read

HIF-1-mediated increase in adipose Angptl4 and the ensuing lipoprotein lipase inactivation may contribute to atherosclerosis in patients with sleep apnea.

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