Choline and Risk of Neural Tube Defects in a Folate-fortified Population

Gary M. Shaw; Richard H. Finnell; Henk J. Blom; Suzan L. Carmichael; Dan Joseph Stein; Wei Yang; Per Magne Ueland

doi:10.1097/ede.0b013e3181ac9fe7

Abstract

1 min read

This is the first study to investigate total choline in NTD-affected pregnancies. Our findings for choline, for which low levels were a risk factor and higher levels were a protective factor for NTDs, may offer a useful clue toward understanding the complex etiologies of NTDs in an era of folic acid fortification of the food supply.

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