Checkpoint Inhibitor–Associated Autoimmune Diabetes Is Distinct From Type 1 Diabetes

Venessa Tsang; Rachel T. McGrath; Roderick Clifton‐Bligh; Richard A Scolyer; Valerie Jakrot; Alexander Guminski; Georgina V. Long; Alexander M. Menzies

doi:10.1210/jc.2019-00423

Abstract

1 min read

CIADM is characterized by sudden permanent β-cell failure occurring after immunotherapy. It is distinct from T1D, usually lacks DAA or T1D-associated HLA-risk haplotypes, and is associated with difficult glycemic control from the onset. As such, CIADM represents a new model of auto-inflammatory β-cell failure.

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Checkpoint Inhibitor–Associated Autoimmune Diabetes Is Distinct From Type 1 Diabetes

Abstract

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