CFH and CFHR structural variants in atypical Hemolytic Uremic Syndrome: Prevalence, genomic characterization and impact on outcome
Article 2023 en
Authors
RP
Rossella Piras
EV
Elisabetta Valoti
MA
Marta Alberti
Abstract
1 min read
In conclusion, these data highlight that uncommon <i>CFH-CFHR</i> SVs are frequent in primary aHUS and quite rare in secondary forms. Notably, genomic rearrangements involving the <i>CFH</i> are associated with a poor prognosis but carriers respond to anti-complement therapy.
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