Central white matter integrity alterations in 2-3-year-old children following prenatal alcohol exposure

Annerine Roos; Catherine J. Wedderburn; Jean‐Paul Fouché; Sivenesi Subramoney; Shantanu H. Joshi; Roger P. Woods; Heather J. Zar; Katherine L. Narr; Dan Joseph Stein; Kirsten A. Donald

doi:10.1016/j.drugalcdep.2021.108826

Abstract

1 min read

Widespread altered white matter microstructural integrity at 2-3 years of age is consistent with findings in neonates in the same and other cohorts, indicating persistence of effects of PAE through early life. Findings also highlight that prenatal tobacco exposure impacts the association of PAE on white matter alterations, amplifying effects in tracts underlying motor function.

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