Cancer Therapy: Smart Probe for Tracing Cancer Therapy: Selective Cancer Cell Detection, Image-Guided Ablation, and Prediction of Therapeutic Response In Situ (Small 36/2015)

A pH-responsive probe containing tetraphenylsilole with aggregation-induced emission characteristics and a pheophorbide A photosensitizer with an aggregation-caused quenching (ACQ) property is developed by B. Z. Tang, B. Liu, and co-workers. On page 4682, they describe how it can be used for self-tracking, selective cancer cell imaging, activated photodynamic ablation of cancer cells, and in-situ prediction of the therapeutic response.