Summary: Pathogenic shifts in the gut microbiota are part of the “ecological” alterations that accompany tumor progression and compromise immunosurveillance. The future management of health and disease including cancer will rely on the diagnosis of such shifts and their therapeutic correction by general or personalized strategies, hence restoring metaorganismal homeostasis.
Romain Daillère, Lisa Derosa, Mélodie Bonvalet, Nicola Segata, Bertrand Routy, Manuela Gariboldi, Eva Budínská, I. Jolanda M. de Vries, Alessio Naccarati, Valérie Zitvogel, Carlos Caldas, Lars Engstrand, Sibylle Loibl, Jacques Fieschi, Lucie Heinzerling, Guido Guido Kroemer, Laurence Zitvogel
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