BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers
Article 2015 en
Authors
HM
Huong Meeks
HS
Honglin Song
KM
Kyriaki Michailidou
Abstract
1 min read
Our study provides evidence that the K3326X variant is associated with risk of developing breast and ovarian cancers independent of other pathogenic variants in BRCA2. Further studies are needed to determine the biological mechanism of action responsible for these associations.
Heather Thorne, Lisa Devereux, Jason Li, Kathryn Alsop, Liz Christie, Courtney T. van Geelen, Nikki Burdett, Kathleen I. Pishas, Noel Woodford, Jodie Leditschke, Mohamed H M A Izzath, Kate Strachan, Greg Young, Rufaro Diana Jaravaza, Mohammed Madadin, Melanie S. Archer, Joanna Glengarry, Linda Iles, Ajith Rathnaweera, Clare Hampson, Khamis Almazrooei,
Discussion(0)
No comments yet. Be the first to comment.