Brain network connectivity assessed using graph theory in frontotemporal dementia

Federica Agosta; Sara Sala; Paola Valsasina; Alessandro Meani; Elisa Canu; Giuseppe Magnani; Stefano F. Cappa; Elisa Scola; Piero Quatto; Mark A. Horsfield; Andrea Falini; Gıancarlo Comı; Massimo Filippi

doi:10.1212/wnl.0b013e31829a33f8

Abstract

1 min read

Global and local functional networks are altered in bvFTD, suggesting a loss of efficiency in information exchange between both distant and close brain areas. Altered brain regions are located in structures that are closely associated with neuropathologic changes in bvFTD. Aberrant topology of the functional brain networks in bvFTD appears to underlie cognitive deficits in these patients.

Related publications

Article2016

Functional Connectome Architecture of Alzheimer’s Disease, Mild Cognitive Impairment and Behavioral Variant of Frontotemporal Dementia: A Graph Analysis Study (P4.028)

Federica Agosta, Elisa Canu, Silvia Basaia, Alessandro Meani, Sebastiano Galantucci, Francesca Caso, Giuseppe Magnani, Roberto Santangelo, Monica Falautano, Gıancarlo Comı, Andrea Falini, Massimo Filippi

Article2017

Brain network connectivity assessed using graph theory in frontotemporal dementia

Abstract

Discussion(0)

Related publications

Functional Connectome Architecture of Alzheimer’s Disease, Mild Cognitive Impairment and Behavioral Variant of Frontotemporal Dementia: A Graph Analysis Study (P4.028)

Brain network connectivity differs in early-onset neurodegenerative dementia

Altered Functional Brain Connectome in the Behavioral Variant of Frontotemporal Dementia (S54.004)

Brain architecture changes across the FTLD spectrum

A brain network model for depression: From symptom understanding to disease intervention