Blocking primary tumor growth and lymphatic metastases by targeting PlGF

Charlotte Fischer; Bart Jonckx; Mieke Dewerchin; Marta Koch; Thien H. Ngo; Patricia Chevron; Hilde Depraetere; Jean–Marie Stassen; Désiré Collen; Lieve Moons; Peter Carmeliet

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Blocking primary tumor growth and metastasis by inhibiting PlGF

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A monoclonal antibody against murine PlGF blocks primary tumor growth in syngeneic mouse tumor models

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142 PLGF Expression By Tumor Stromal Cells Is Induced Via Tumor Cell-Tumor Stromal Crosstalk and Substantially Contributes to Tumor Growth

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