Bisphosphonate therapy for children and adolescents with secondary osteoporosis

Leanne M. Ward; Andrea C. Tricco; Phuc-Nhi Phuong; Ann Cranney; Nick Barrowman; Isabelle Gaboury; Frank Rauch; Peter Tugwell; David Moher

doi:10.1002/14651858.cd005324.pub2

Abstract

1 min read

The results justify further evaluation of bisphosphonates among children with secondary osteoporosis. However, the evidence does not support bisphosphonates as standard therapy. Short-term (3 years or less) bisphosphonate use appears to be well-tolerated. An accepted criterion for osteoporosis in children, a standardized approach to BMD reporting, and examining functional bone health outcomes (e.g., fracture rates) will allow for appropriate comparisons across studies.

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