Beneficial Effect of TGFβ Antagonism in Treating Diabetic Nephropathy Depends on When Treatment Is Started
Article 2006 en
Authors
AB
Ariela Benigni
CZ
Carla Zoja
MC
Marco Campana
Abstract
1 min read
Renoprotective effect of TGFbeta antagonism crucially depends on the time at which treatment started. Effectiveness of early treatment with 1D11 would indicate that TGFbeta is a major mediator of damage in early diabetes. To tackle the renal damage in the phase of advanced disease, a combined treatment with ACE inhibitor is needed.
Ariela Benigni, Carla Zoja, Daniela Corna, Cristina Zatelli, Sara Conti, Marco Campana, Elena Gagliardini, Daniela Rottoli, Cristina Zanchi, Mauro Abbate, Steve Ledbetter, Giuseppe Remuzzi
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