Automated parallel investigations of polymerization kinetics by online monitoring of GC and GPC

Gel permeation chromatog. (GPC) and gas chromatog. (GC) were successfully introduced into a high-throughput workflow for the online monitoring of polymn. kinetics. The feasibility and limitations of online GPC equipped with a high-speed column was evaluated by measuring poly(styrene) stds. and comparison of the results with regular offline GPC measurements. The reliability of the online GC characterization was studied by monitoring the cationic ring-opening-polymn. of 2-ethyl-2-oxazoline, whereby polymn. kinetics were detd. with both online and offline GC