Autologous hematopoietic stem cell transplantation in multiple sclerosis

Gianluigi Mancardi; Maria Pia Sormani; Francesca Gualandi; Albert Saiz; Enric Carreras; E. Merelli; Amedea Donelli; Alessandra Lugaresi; Paolo Di Bartolomeo; Maria Rosa Rottoli; Alessandro Rambaldi; Maria Pia Amato; Luca Massacesi; Massimo Di Gioia; Luisa Vuolo; Daniela Currò; Luca Roccatagliata; Massimo Filippi; Umberto Aguglia; Pasquale Iacopino; Dominique Farge; Riccardo Saccardi; Elisabetta Capello; Antonio Uccelli; F. Bagigalupo; Anna Repice; Emilio Portaccio; A. Barillaro; Carlo Russo; Giovanna De Luca; D. Farina; Armando Tartaro; Yolanda Blanco; Juan Berenguer; Pablo Diego Bresciani; Aurora Cuoghi; P. Zonari

doi:10.1212/wnl.0000000000001329

Abstract

1 min read

Intense immunosuppression followed by AHSCT is significantly superior to MTX in reducing MRI activity in severe cases of MS. These results strongly support further phase III studies with primary clinical endpoints. The study was registered as EUDRACT No. 2007-000064-24.

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