Associations of leucocyte subtypes and platelet parameters with kidney cancer risk in the UK Biobank cohort

Sofia Christakoudi; Konstantinos K Tsilidis; Marc J. Gunter; Elio Riboli

doi:10.1186/s12950-025-00458-6

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Associations of leucocyte subtypes and platelet parameters with kidney cancer risk in the UK Biobank cohort

Article 2025 en

Abstract

1 min read

Our findings support two separate longer-acting pathways in kidney cancer development- a pathway related to general rather than abdominal obesity and an immune-cell-related pathway involving neutrophils assisted by activated platelets, as well as a cancer-induced thrombo-inflammation closer to kidney cancer diagnosis.

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