Association between Oxidative Balance Scores (OBS) and Gamma- Glutamyltransferase (GGT) among US adults in NHANES 2013– 2018

<title>Abstract</title> The Oxidative Balance Score (OBS) quantifies the balance between antioxidants and pro-oxidants, which is influenced by diet and lifestyle, and is used to evaluate the overall oxidative stress status. Elevated levels of γ-glutamyl transferase (GGT) are considered a primary indicator of oxidative stress. This study aims to explore the association between OBS and GGT using data from the National Health and Nutrition Examination Survey (NHANES) conducted between 2013 and 2018. A total of 7,998 people were included in the study. Research has revealed a significant linear negative correlation was found between OBS scores and GGT. Fully adjusted weighted logistic regression analysis showed that each unit increase in OBS was associated with a 3% decrease in the odds of abnormal GGT [OR = 0.97, 95%CI: 0.95, 0.99, P &lt; 0.001]. By exploring this link, this could provide valuable insights into developing preventive strategies and interventions for GGT abnormalities.