Assessment of Brain White Matter Fiber Bundle Atrophy in Patients with Friedreich Ataxia

Elisabetta Pagani; Andrea Ginestroni; Riccardo Della Nave; Federica Agosta; Fabrizio Salvi; Giuseppe De Michele; Silvia Piacentini; Massimo Filippi; Mario Mascalchi

doi:10.1148/radiol.10091742

Abstract

1 min read

Findings of this study show that it is feasible to obtain in vivo atrophy estimates of specific brain WM fiber bundles in patients with Friedreich ataxia and that such estimates correlate with patients' clinical status. This approach has the potential to provide new information that is likely to improve the understanding of the pathophysiology of inherited ataxias.

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